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Anesth Pain Med > Volume 10(3); 2015 > Article
Neuroanesthesia
Anesthesia and Pain Medicine 2015;10(3):192-195.
DOI: https://doi.org/10.17085/apm.2015.10.3.192    Published online July 31, 2015.
The relationship between the serum lactate level and in-hospital mortality after decompressive craniectomy in traumatic brain Injury
Wol Seon Jung, Dongchul Lee, Young Jin Chang, Chun Kon Park, Youn Yi Jo
Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Incheon, Korea. endless37@gilhospital.com
Received: 13 January 2015   • Revised: 27 March 2015   • Accepted: 11 April 2015
Abstract
BACKGROUND
The patients with traumatic brain injury showed ischemia due to increased intracranial pressure. This study evaluated the relationship of pre-anesthetic serum lactate level with in-hospital mortality.
METHODS
The archived medical records of 121 patients were retrospectively reviewed. Demographics and preoperative serum lactate level were analyzed.
RESULTS
Of the 121 patients, 32 patients expired in the hospital after decompressive craniectomy. Preoperative serum lactate levels were 3.2 +/- 2.2 mmol/L in the survivors and 5.4 +/- 3.0 mmol/L in the dead (P = 0.001), and the receiver operating characteristic curve revealed that a cut off value of 3.60 mmol/L was reasonable for predicting mortality.
CONCLUSIONS
Preoperative serum lactate level is highly correlated with in-hospital mortality after decompressive craniectomy in traumatic brain injury.
Key Words: Mortality, Serum lactate, Traumatic brain injury
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