Brugada syndrome manifested in postoperative period: A case report

Lee, Ju Hyun; Ro, Young Jin; Yang, Hong Seuk

Case Report

General Article

Anesthesia and Pain Medicine 2013;8(3):203-207.
Published online July 30, 2013.

Brugada syndrome manifested in postoperative period: A case report

Ju Hyun Lee, Young Jin Ro, Hong Seuk Yang

Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. hsyang@amc.seoul.kr

Abstract

We describe here a woman with Brugada syndrome revealed in postoperative period. A 48-year-old woman who underwent open biopsy of a tumor on her left distal femur under general anesthesia experienced post-surgical palpitations and chest discomfort. On the following day, an electrocardiogram showed coved type ST elevation with T inversion on V1 and V2 without any structural heart disease. After we confirmed it by a flecainide provocation test, the patient was diagnosed with Brugada syndrome. Genetic analysis showed c.3578G > A (p.Arg1193Gln) variant in the SCN5A gene. She underwent successful curettage and internal fixation under a single-shot spinal anesthesia without any adverse events.

Key Words: Brugada syndrome, General anesthesia, Genetic analysis