Hyperamylasemia following the trans-sphenoidal resection of pituitary tumor: can propofol-remifentanil TIVA cause postoperative hyperamylasemia?: A case report

Lee, Hae Mi; Kim, Seung Dong; Kim, Oh Ryong; Jee, Dae Lim

Case Report

Neuroanesthesia

Anesthesia and Pain Medicine 2011;6(2):160-163.
Published online April 30, 2011.

Hyperamylasemia following the trans-sphenoidal resection of pituitary tumor: can propofol-remifentanil TIVA cause postoperative hyperamylasemia?: A case report

Hae Mi Lee, Seung Dong Kim, Oh Ryong Kim, Dae Lim Jee

¹Department of Anesthesia and Pain Medicine, Yeungnam University, Daegu, Korea. adjee@medical.yeungnam.ac.kr
²Department of Neurosurgery, School of Medicine, Yeungnam University, Daegu, Korea.

Abstract

The trans-sphenoidal resection of a recurred pituitary tumor was performed in a 42 years old man under general anesthesia with propofol and remifentanil. Neither massive bleeding nor hypotension was observed intraoperatively, but bradycardia was sustained over five hours. The patient did not suffer from hypertriglyceridemia and there was no evidence of drug toxicity or vigorous intervention during the surgery, however hyperamylasemia was observed one day after the surgery. It is presumed that vagal stimulation by propofol and remifentanil infusion might induce bradycardia and abnormal pancreatic enzyme secretion consequently.

Key Words: Bradycardia, Hyperamylasemia, Propofol