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Neuromuscular Physiology and Pharmacology
Anesthesia and Pain Medicine 2011;6(1):75-78.
Published online January 31, 2011.
Comparison of the effects of preoxygenation between pregnant and non-pregnant patients
Dong Yeon Kim, Seol Joo Jeong, Jong Hak Kim
Department of Anesthesiology and Pain Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
Preoxygenation is a standard anesthetic technique using 100% oxygen for the prevention of hypoxia during the induction of anesthesia. Measuring end-tidal oxygen is the most useful indicator for determining the end-point of preoxygenation. We studied the effects of preoxygenation between pregnant and non-pregnant patients during 5 min of tidal volume breathing.
Non-pregnant women who were scheduled for general surgery (Group I, n = 25) and pregnant women who were scheduled for elective cesarean section (Group II, n = 20) were explained the technique of preoxygenation, which was conducted with 100% oxygen during 5 min of tidal volume breathing. End-tidal oxygen concentration was measured at 10 sec intervals for 5 min, simultaneously.
Group II showed significantly higher end-tidal oxygen concentration than Group I from 30 sec to 170 sec during preoxygenation (P < 0.05). The mean time required for end-tidal oxygen concentration > or =90% was 110.0 +/- 31.7 sec for Group II and 152.8 +/- 34.5 sec for Group I. Therefore, Group II showed a significantly shorter time than Group I (P < 0.05).
We concluded that the time for complete preoxygenation was shorter in pregnant patients compared to non-pregnant patients.
Key Words: Oxygen concentration, Pregnancy, Preoxygenation

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