Vancomycin-induced Hypersensitivity Reaction with Slow Infusion : A case report

Yang, Cheol Sueng; Koo, Min Seok; Kwak, Ho Sung; Lee, Myung Ae; Lee, Hyun Ha

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Case Report

Anesthetic Pharmacology

Anesthesia and Pain Medicine 2008;3(3):183-185.
Published online July 30, 2008.

Vancomycin-induced Hypersensitivity Reaction with Slow Infusion : A case report

Cheol Sueng Yang, Min Seok Koo, Ho Sung Kwak, Myung Ae Lee, Hyun Ha Lee

Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea. clinician@naver.com

Abstract

Vancomycin is a bacteriocidal antibiotic experiencing a resurgence of utility because of increasing clinical problems with methicillinresistant staphylcoccal infections. Vancomycin can cause two types of hypersensitivity reactions, the red man syndrome and anaphylaxis. There is a consensus that slow intravenous administration of vancomycin should minimize the risk of infusion related adverse effects. We report a case of vancomycin hypersensitivity reaction with slow infusion of vancomycin.

Key Words: adverse reaction, anaphylaxis, red man syndrome, vancomycin

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