Effect of Low-dose Rocuronium on Tracheal Intubating Conditions during Induction of 8 vol% Sevoflurane with Remifentanil

Son, Youn Suk; Chung, Kyu Don; Cho, Hyun Sook; Lee, Sang Mook; Ryu, Keon Hee; Kim, Su Hwa

Clinical Research

General Article

Anesthesia and Pain Medicine 2007;2(4):257-261.
Published online October 30, 2007.

Effect of Low-dose Rocuronium on Tracheal Intubating Conditions during Induction of 8 vol% Sevoflurane with Remifentanil

Youn Suk Son, Kyu Don Chung, Hyun Sook Cho, Sang Mook Lee, Keon Hee Ryu, Su Hwa Kim

Department of Anesthesiology and Pain Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. nmoney@korea.com

Abstract

BACKGROUND
We evaluated the effect of low doses of rocuronium on tracheal intubating conditions and hemodynamic changes during induction of anesthesia with 8 vol% sevoflurane and remifentanil 1microg/kg. METHODS: Eighty four patients were randomized into one of three groups; Group I, II, III. Each group received normal saline, 0.3, 0.45 mg/kg of rocuronium respectively. Predetermined drugs for each group and remifentanil 1microg/kg were administered during induction of 8 vol% sevoflurane. After induction of 8 vol% sevoflurane, tracheal intubation was preformed. The tracheal intubation conditions and hemodynamic responses to tracheal intubation were assessed. RESULTS: Tracheal intubation was successful in all patients. The incidence of clinically acceptable intubating conditions was 79% in Group I, 100% in Group II, and 100% in Group III. There was no significant difference in intubating condition between Group II and Group III. The hemodynamic responses to tracheal intubation were blunted in all groups. CONCLUSIONS: After induction with 8 vol% sevoflurane and remifentanil 1microg/kg, low-dose rocuronium provides more satisfactory tracheal intubation conditions.

Key Words: intubation condition, remifentanil, rocuronium, sevoflurane