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General Article
Anesthesia and Pain Medicine 2007;2(3):156-159.
Published online July 31, 2007.
The Influence of Nitrous Oxide on Postoperative Bowel Function Recovery for Gynecologic Patients
Seung Ho Kim, Jie Eun Song, Kuem Hee Chung, Heon Rak Lee, Min Gu Kim, Hyeon Jeong Yang
Department of Anesthesiology and Pain Medicine, Pochon CHA University College of Medicine, Pocheon, Korea. yanghj@medigate.net
Abstract
BACKGROUND
Nitrous oxide may cause distension of the intestine. We studied the influence of nitrous oxide on the recovery of bowel function and the incidence of complications of bowel distension. METHODS: Fifty patients scheduled for abdominal hysterectomy were anesthetized with sevoflurane and oxygen and were randomly assigned to be given 50% nitrous oxide (n = 25) or 50% air (n = 25) in two groups. A surgeon assessed the closing condition. Patients reported pain, nausea and vomiting after surgery. The lapse of time before the passing of flatus was recorded. RESULTS: There was no difference between the two groups with respect to body weight, duration of surgery, alfentanil and atracurium requirements, pain score, nausea and vomiting, and closing condition. The time elapsing before the passing of flatus was significantly greater for the patients that received nitrous oxide. CONCLUSIONS: Our results suggest that avoiding nitrous oxide administration during prolonged intraabdominal surgery shortens the time for recovery of bowel function.
Key Words: air, bowel, function, nitrous, oxide
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