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Anesthetic Pharmacology
Anesthesia and Pain Medicine 2006;1(1):23-28.
Published online July 30, 2006.
Repeated Sedation with Intravenous Propofol in a Brain Tumor Patient during ConsecutiveRadiation Therapy : A case report
Gyeong Jo Byeon, Hyeon Jeong Lee, Jae Young Kwon
Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University, Busan, Korea. jykwon@pusan.ac.kr
Abstract
Deep sedation or general anesthesia has been frequently required daily radiation therapy in pediatric patients. We experienced repeated sedation with propofol in a 16-year-old patient who underwent consecutive radiation therapy due to brain tumor. During treatment, the patient showed increased susceptibility to propofol. The brain magnetic resonance imaging (MRI) showed gradual increase in size of brain tumor regardless of radiation therapy. The increased susceptibility of propofol may be related with growth of brain tumor.
Key Words: brain tumor, propofol susceptibility, radiation therapy
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